In this study, orlistat produced a significant reduction inweight and total testosterone. The reduction in total testosteronewas similar to that seen after treatment with metformin. Therefore,orlistat may prove to be a useful adjunct in the treatment ofPCOS.
The polycystic ovary syndrome (PCOS) affects five to 10 percent of reproductive age women, and is the most common cause of female infertility due to anovulation in the United States.